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Updated: Feb 28, 2026
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Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
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[Optical coherence tomography angiography in glaucoma diagnosis]
1Institute of Professional Development, Federal Medical-Biological Agency, 15 Gamalei St., Moscow, Russian Federation, 123098.
Vestnik Oftalmologii
|June 22, 2017
Summary
Optical coherence tomography angiography (OCTA) shows reduced retinal blood flow in glaucoma patients. This imaging technique may improve early glaucoma diagnosis and monitoring by assessing ocular perfusion.
Area of Science:
- Ophthalmology
- Medical Imaging
- Vascular Biology
Background:
- Vascular dysfunction is implicated in glaucomatous optic neuropathy.
- Early diagnosis and monitoring of glaucoma are crucial for patient management.
- Novel imaging techniques are needed to assess ocular perfusion.
Purpose of the Study:
- To evaluate Optical Coherence Tomography Angiography (OCTA) for assessing retinal, optic nerve head (ONH), and choroidal perfusion in glaucoma.
- To explore OCTA's potential in early glaucoma diagnosis and disease monitoring.
Main Methods:
- Utilized Optical Coherence Tomography Angiography (OCTA), a non-invasive imaging technique.
- Employed the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm for blood flow evaluation.
- Assessed retinal and choroidal blood flow in peripapillary and macular regions.
Main Results:
- OCTA revealed decreased retinal blood flow in glaucoma patients.
- Peripapillary blood flow index correlated better with visual field indices than ONH morphometry.
- OCT angiography demonstrates potential for ONH blood flow assessment.
Conclusions:
- OCTA is a promising tool for evaluating ocular perfusion in glaucoma.
- OCTA may enhance early glaucoma detection and monitoring by assessing vascular changes.
- Further research into OCTA's role in understanding glaucoma pathogenesis is warranted.
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