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Updated: Feb 28, 2026
07:27
Olfactory Assays for Mouse Models of Neurodegenerative Disease
Published on: August 25, 2014
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[Methods for evaluating of olfactory function in patients with Parkinson's disease]
I A Zhukova1, N G Zhukova1, O P Izhboldina1
1Siberian State Medical University, Tomsk.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|June 22, 2017
Summary
Olfactory disorder is an early sign of Parkinson's disease (PD). Simple smell tests can aid in the early diagnosis and differential diagnosis of PD and other extrapyramidal system diseases.
Area of Science:
- Neurology
- Neuroscience
- Ophthalmology
Context:
- Olfactory disorder is a significant non-motor symptom in Parkinson's disease (PD).
- It is recognized as one of the earliest indicators of the disease.
- The role of olfactory dysfunction in PD pathogenesis is increasingly studied.
Purpose:
- To highlight the importance of olfactory testing in the diagnostic process for Parkinson's disease (PD).
- To advocate for the inclusion of structured olfactory tests in the diagnostic algorithm for early PD detection.
- To emphasize the utility of smell tests in the differential diagnosis of extrapyramidal system diseases.
Summary:
- Olfactory dysfunction is a key early non-motor symptom of Parkinson's disease (PD).
- The abstract reviews literature supporting the use of olfactory function tests for PD diagnosis.
- Structured smell tests are proposed as a valuable tool for early PD detection and differential diagnosis.
Impact:
- Integrating olfactory tests can improve the early and accurate diagnosis of Parkinson's disease (PD).
- This approach can enhance the differential diagnosis of neurological disorders affecting the extrapyramidal system.
- Standardized olfactory assessments may become a crucial component of neurological diagnostic protocols.
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