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Updated: Feb 28, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Sinonasal teratocarcinosarcoma: a case report
Yi Chao Foong1,2, Vince Murdolo3, Nusa Naiman4
1Department of Radiation Oncology, Royal Hobart Hospital, 17 Liverpool St, Hobart, Tasmania, 7000, Australia. yi.foong@dhhs.tas.gov.au.
Background:
Sinonasal teratocarcinosarcoma is a rare and aggressive malignancy with histological features of both carcinosarcoma and teratoma. The optimal management of this malignancy is unclear, with most patients being managed by a combination of surgery and radiotherapy.
Case Presentation:
We describe an 83-year-old white woman with sinonasal teratocarcinosarcoma of her left nasal cavity treated with surgical debulking initially with radiological evidence of residual disease which was treated with radiotherapy (60 Gy in 30 fractions). A follow-up examination at 2 years showed no evidence of recurrence.
Conclusions:
In cases of sinonasal teratocarcinosarcoma with residual disease post-surgery, radiotherapy alone can be an effective option.

