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A Case Report of Psychoactive Drugs Aggravating and Alleviating Meige Syndrome
Shimiao Zhao1,2, Yingchun Zhang1, Luoyi Xu1
1Department of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang University School of Medical, and the Collaborative Innovation Center for Brain Science, Hangzhou, Zhejiang, China.
Abstract:
The present case report described a 61-year-old female patient who was diagnosed as Meige syndrome with double eyelid spasm, anxiety and insomnia. After she was treated with psychoactive drugs, it was found that clonazepam tablets in the benzodiazepine class and dopamine antagonist olanzapine tablets aggravated double eyelid spasm; while eszopiclone tablets as a specificity γ-aminobutyric acid receptor binding drug alleviated this condition. The present case suggests that psychoactive drugs have both positive and negative effects on treating Meige syndrome. As for the patients who also have emotion disorder, their conditions should be observed carefully when choosing which psychoactive drug to use. The specificity γ-aminobutyric acid receptor binding drugs should be the prime choice, such as eszopiclone.
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