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Low-Grade Papillary Schneiderian Carcinoma: A Case Report
Hui-Jeong Jeong1, Jin Roh1, Bong-Jae Lee2
1Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43 gil, Songpa-gu, Seoul, 05505, South Korea.
Head and Neck Pathology
|June 23, 2017
Summary
A rare sinonasal carcinoma, mimicking oncocytic papilloma, was diagnosed in a patient with nasal obstruction. This low-grade papillary Schneiderian carcinoma requires awareness for accurate diagnosis and treatment.
Area of Science:
- Pathology
- Oncology
- Otorhinolaryngology
Background:
- Schneiderian epithelium lines the sinonasal tract and can develop into carcinomas.
- Sinonasal tumors present diagnostic challenges, often requiring detailed histopathological analysis.
Observation:
- A 42-year-old woman presented with nasal obstruction and rhinorrhea, with imaging revealing a mass in the nasal cavity and paranasal sinuses.
- Histopathological examination of the resected mass showed invasive growth of bland epithelial cells with oncocytic features.
Findings:
- The tumor exhibited papillary and inverted architectures, with neoplastic cells displaying uniform nuclei and abundant cytoplasm.
- The features were consistent with a low-grade papillary Schneiderian carcinoma, distinct from Schneiderian papilloma.
Implications:
- Accurate differentiation between low-grade papillary Schneiderian carcinoma and Schneiderian papilloma is crucial for appropriate patient management.
- Increased awareness of this rare sinonasal malignancy is important for clinicians and pathologists.
