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Updated: Feb 28, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Approach to thyroid carcinoma in pregnancy
Cristina Modesti1, Paola Aceto2, Lucia Masini3
1Department of Anesthesia and Intensive Care, Agostino Gemelli Hospital, Catholic University of the Sacred Heart, Rome, Italy. cristina.modesti@unicatt.it.
Thyroid cancer in pregnant women can be safely treated with thyroidectomy using local anesthesia and conscious sedation. This approach offers a viable option for managing thyroid malignancy during pregnancy.
Area of Science:
- Oncology
- Anesthesiology
- Obstetrics
Background:
- Thyroid carcinoma is a common cancer, and the second most frequent malignancy diagnosed during pregnancy.
- Managing thyroid cancer in pregnant patients presents significant diagnostic and therapeutic challenges.
- Surgical intervention for thyroid cancer during pregnancy is common despite a lack of consensus on optimal approaches.
Purpose of the Study:
- To evaluate the safety and efficacy of thyroidectomy under local anesthesia with conscious sedation in pregnant patients.
- To explore alternative sedation methods like hypnosis for thyroid cancer surgery during pregnancy.
Main Methods:
- A retrospective review of 18 pregnant patients who underwent thyroidectomy between 2000 and 2016.
- Surgical procedure utilized local anesthesia (cervical plexus block) combined with conscious sedation (benzodiazepines and opiates).
Main Results:
- The combined technique of cervical plexus block and conscious sedation proved to be a safe method for thyroidectomy in pregnant patients.
- The study highlights a 15-year experience with this anesthetic approach.
Conclusions:
- Thyroidectomy under local anesthesia with conscious sedation is a safe and effective option for treating thyroid cancer in pregnant women.
- Hypnosis is suggested as a potential alternative to pharmacological sedation, particularly for patients seeking to avoid intravenous drugs.
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