Related Experiment Video
Updated: Feb 27, 2026
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Atypical Primary Cutaneous Rosai Dorfman Disease: A Case Report
Anna E Kinio1, Michael A Sawchuk2, Melanie Pratt1,2
11 Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Background:
Rosai Dorfman disease (RDD) is a rare disorder that typically presents with bilateral cervical lymphadenopathy and follows a benign course.
Objective:
We present a case of late-onset atypical primary cutaneous RDD that is resistant to treatment modalities described in the literature.
Methods:
Case report.
Results:
An 84-year-old woman presented with a 7-year history of cutaneous lesions histologically consistent with RDD. She later failed initial treatments of acitretin and thalidomide.
Conclusion:
Physicians must be aware of unusual presentations of RDD. Also, further treatment options must be explored for patients resistant to classical management of RDD.
Related Concept Videos
01:03Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
01:30Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:23Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...