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Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis
Robert W Foley1, Nathan T Tagg2, Matthew K Schindler2
1Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; School of Medicine, University College Dublin, Dublin, Ireland.
Abstract:
Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.

