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Jan S Schenkel1, Heinz-Theo Lübbers, Claudio Rostetter

  • 1Clinique universitaire de chirurgie maxillo-faciale, Hôpital de l’Ile, Hôpital universitaire de Berne, Bern, Switzerland.

Swiss Dental Journal
|June 23, 2017
PubMed
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Oral lichen planus, an inflammatory disease, can cause painful mouth sores and may transform into cancer. Treatment options include corticosteroids, with regular check-ups essential due to malignancy risk.

Area of Science:

  • Oral medicine
  • Dermatology
  • Immunology

Background:

  • Oral lichen planus (OLP) is a common T-cell mediated inflammatory condition affecting the oral mucosa.
  • It is characterized by potentially painful lesions, including ulcers and Wickham's striae.
  • A significant concern with OLP is its potential for malignant transformation.

Purpose of the Study:

  • To review the clinical presentation and management strategies for oral lichen planus.
  • To highlight effective treatment options and the importance of follow-up.
  • To discuss the risk of malignant transformation associated with OLP.

Main Methods:

  • Literature review of oral lichen planus management.
  • Analysis of treatment efficacy for various therapeutic agents.
Keywords:
Traitement médicamenteuxlichen plan buccal

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  • Discussion of diagnostic criteria and follow-up protocols.

    • Main Results:

    • Topical corticosteroids, particularly Clobetasol, are primary treatments.
    • Immunosuppressive drugs, retinoids, hyaluronic acid, and aloe vera show therapeutic success.
    • Systemic corticosteroids may be required for refractory cases.

    Conclusions:

    • Effective management of oral lichen planus involves a stepwise approach, often starting with topical therapies.
    • Regular monitoring is crucial due to the inherent risk of malignant transformation.
    • A combination of treatments may be necessary for optimal patient outcomes.