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Updated: Feb 27, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Anesthetic Management of Patients Undergoing Percutaneous Endocardial and Epicardial Left Atrial Appendage Occlusion
Zeena Husain1, Payam Safavi-Naeini2, Abdi Rasekh2
11 Baylor College of Medicine, Houston, TX, USA.
Insights
Atrial fibrillation patients can now consider left atrial appendage occlusion devices as an alternative to blood thinners for stroke prevention. These innovative devices offer a promising option for managing thromboembolic risk in adults with this common heart arrhythmia.
Area of Science:
- Cardiology
- Medical Devices
- Interventional Procedures
Background:
- Atrial fibrillation (AF) is a prevalent cardiac arrhythmia in adults.
- Heart failure and thromboembolic events are common comorbidities in AF patients.
- Chronic anticoagulation is standard but carries risks and limitations.
Purpose of the Study:
- To review percutaneous left atrial appendage occlusion (LAAO) devices as an alternative to anticoagulation in AF.
- To detail the procedures and anesthetic considerations for LAAO devices.
- To discuss the management of adverse events associated with LAAO.
Main Methods:
- Review of percutaneous LAAO device procedures.
- Description of anesthetic management for LAAO.
- Analysis of adverse event management strategies.
Main Results:
- Several LAAO devices, including WATCHMAN and LARIAT, have been developed.
- Some devices demonstrate non-inferiority to anticoagulation in preventing strokes.
- Detailed procedural and anesthetic information is provided.
Conclusions:
- LAAO devices represent a significant innovation for stroke risk reduction in AF.
- These devices offer a viable alternative to chronic anticoagulation for select patients.
- Understanding procedural nuances and adverse event management is crucial for successful LAAO implementation.
Abstract:
Atrial fibrillation is the most common cardiac arrhythmia in adults affecting almost 6 million adults in the United States. The 2 most common comorbidities associated with atrial fibrillation are heart failure and thromboembolic events. Heart failure symptoms may be treated with rate control, antiarrhythmic medications or by catheter ablation. Unfortunately, despite optimal medical management, thromboembolic events still occur. Recently, there has been a great deal of interest and innovation in finding an alternative to chronic anticoagulation. Several percutaneous left atrial appendage occlusion devices have been developed over recent years, some of which have proven to be noninferior to anticoagulation in preventing strokes in atrial fibrillation patients. The 2 most widely used left atrial appendage occlusion devices are the WATCHMAN (Atritech Inc, Plymouth, MN, USA) and the LARIAT (SentreHEART, Palo Alto, CA, USA) devices. After a detailed description of the procedures, the anesthetic considerations of each procedure and management of specific adverse events are discussed within this review.
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