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Updated: Feb 27, 2026

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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TWEAK/Fn14 signaling in tumors

Guanglei Hu1, Weihui Zeng1, Yumin Xia1

  • 1Department of Dermatology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine
|June 23, 2017
PubMed
Summary

Tumor necrosis factor-related weak inducer of apoptosis (TWEAK) and its receptor Fn14 are upregulated in solid tumors, promoting cancer progression. Targeting this TWEAK/Fn14 pathway shows promise for future cancer therapies.

Keywords:
Fn14TWEAKsignaling pathwaytargeted therapytumor

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