Infections Associated With Streptococcus Constellatus in Children

Howard Faden1, Mustafa Mohmand

  • 1From the *Department of Pediatrics and Division of Infectious Diseases, University at Buffalo School of Medicine and Biomedical Sciences, and †Department of Pediatrics and Division of Infectious Diseases, Women and Children's Hospital, Buffalo, New York.

Insights

Streptococcus constellatus, a type of viridans Streptococcus, is linked to abscesses in children, particularly those with perforated appendicitis. This finding is relevant for pediatric infectious disease research.

Area of Science:

  • Microbiology
  • Pediatric Infectious Diseases
  • Clinical Bacteriology

Background:

  • Streptococcus constellatus is a member of the viridans Streptococcus group, specifically within the Anginosus group.
  • Viridans streptococci are known commensals but can be opportunistic pathogens.

Purpose of the Study:

  • To investigate the association between Streptococcus constellatus and abscess formation in pediatric patients.
  • To determine the clinical context, such as appendicitis, in which S. constellatus infections occur in children.

Main Methods:

  • Retrospective analysis of pediatric cases involving Streptococcus constellatus.
  • Review of clinical data, including diagnoses, surgical findings, and microbiological results.

Main Results:

  • Streptococcus constellatus was identified in abscesses in 37 pediatric patients.
  • A significant proportion (80%) of these children had acute appendicitis with perforation.
  • Abscess formation was noted in 50% of the appendicitis cases.
  • All affected children were 3 years of age or older.

Conclusions:

  • Streptococcus constellatus is implicated as a causative agent in pediatric abscesses.
  • The bacterium is frequently associated with complicated appendicitis, specifically perforation and subsequent abscess formation.
  • Clinical vigilance for S. constellatus is warranted in pediatric cases of appendicitis, especially in children aged 3 years and above.

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