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Total Synthesis of Huperzine Q

Shun Tanimura1,2, Satoshi Yokoshima1, Tohru Fukuyama1

  • 1Graduate School of Pharmaceutical Sciences, Nagoya University , Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.

Organic Letters
|June 23, 2017
PubMed

Abstract:

The total synthesis of huperzine Q was accomplished. The synthesis features the construction of the cis-hydrindane skeleton via a Diels-Alder reaction and a ring contraction reaction of an epoxyketone.

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