Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fatigue01:21

Fatigue

893
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
893
Survey Safety01:28

Survey Safety

434
Surveying near highways, rough terrain, or power lines involves significant risks. Working along highways is particularly dangerous and requires the use of warning signs and flagmen. It is safest to avoid working directly on roads and use offsets whenever possible. When highway work is unavoidable, it must follow all safety guidelines. Surveyors should wear bright clothing, such as orange reflective vests, to ensure visibility to motorists, coworkers, and hunters. In construction zones, wearing...
434
Design Consideration01:22

Design Consideration

609
Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key...
609
Fatigue Strength of Concrete01:22

Fatigue Strength of Concrete

626
Fatigue, in the context of materials science and engineering, refers to the weakening or failure of a material caused by repeatedly applied loads, even if these loads are below the strength limit of the material. Fatigue strength in concrete is a critical property that influences its durability and longevity. Concrete can fail in two ways due to fatigue. Static fatigue or creep rupture occurs under a constant load or one that increases slowly. The other failure mode is due to cyclical or...
626
Hazard Rate01:11

Hazard Rate

464
The hazard rate, also known as the hazard function or failure rate, is a statistical measure used to describe the instantaneous rate at which an event occurs, given that the event has not yet happened. From a probabilistic perspective, it represents the likelihood that a subject will experience the event in a very small time interval, conditional on surviving up to the beginning of that interval. In terms of frequency, the hazard rate can be viewed as the ratio of the number of events to the...
464
Narcolepsy01:07

Narcolepsy

638
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
638

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of relapsed/refractory peripheral T-cell lymphoma in the modern era: impact of stem cell transplant and novel agents.

Leukemia & lymphoma·2025
Same author

Moe Kura: a longitudinal study of mother and child sleep and well-being in Aotearoa New Zealand.

Journal of the Royal Society of New Zealand·2024
Same author

Nodal T-Cell Lymphoma Transdifferentiated from Mantle Cell Lymphoma with Epstein-Barr Virus Infection.

Pathobiology : journal of immunopathology, molecular and cellular biology·2024
Same author

Biotrapping Ureolytic Bacteria on Sand to Improve the Efficiency of Biocementation.

ACS applied materials & interfaces·2024
Same author

Exploring older care recipients' sleep status as a predictor for informal carer distress: evidence from New Zealand's interRAI home care assessment data.

BMJ open·2023
Same author

Deposition of complement components C5b-9 and MASP2 in tissues is not a feature of GVHD and may assist in discriminating GVHD from thrombotic microangiopathy following allogenic transplantation.

Bone marrow transplantation·2023

Related Experiment Video

Updated: Feb 27, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

12.9K

Preparing Safety Cases for Operating Outside Prescriptive Fatigue Risk Management Regulations.

Philippa Gander, Jim Mangie, Lora Wu

    Aerospace Medicine and Human Performance
    |June 24, 2017
    PubMed
    Summary

    Transport operators can develop safety cases to manage fatigue risks outside regulations. This method, including risk assessment and mitigation, allows flexibility in pilot rest breaks, proving the third break isn't always superior.

    More Related Videos

    The Effect of Anti-Fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model
    05:38

    The Effect of Anti-Fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model

    Published on: April 12, 2024

    613
    A Mouse Model of Fatigue Induced by Peripheral Irradiation
    04:15

    A Mouse Model of Fatigue Induced by Peripheral Irradiation

    Published on: March 17, 2017

    8.3K

    Related Experiment Videos

    Last Updated: Feb 27, 2026

    Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
    08:36

    Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

    Published on: August 8, 2019

    12.9K
    The Effect of Anti-Fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model
    05:38

    The Effect of Anti-Fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model

    Published on: April 12, 2024

    613
    A Mouse Model of Fatigue Induced by Peripheral Irradiation
    04:15

    A Mouse Model of Fatigue Induced by Peripheral Irradiation

    Published on: March 17, 2017

    8.3K

    Area of Science:

    • Aviation safety
    • Human factors in transportation
    • Occupational health

    Background:

    • Transport operators must justify fatigue risk management outside regulations.
    • A structured safety case method is detailed for compliance.
    • This enables operational flexibility in crew rest scheduling.

    Purpose of the Study:

    • To present a method for constructing a successful safety case for operating outside prescriptive fatigue management regulations.
    • To demonstrate how this method allows for flexible rest break choices for pilots.
    • To validate the effectiveness of the proposed safety case approach.

    Main Methods:

    • The safety case method involves defining scope, risk assessment, mitigation strategies, and ongoing monitoring.
    • Scope included analyzing 4151 scheduled flights to estimate fatigue risk.
    • Risk assessment utilized existing literature and pre-regulation pilot data (6% chose third break).

    Main Results:

    • A prospective survey (N=280) confirmed the third rest break is not consistently superior for sleep or fatigue.
    • The safety case successfully summarized existing fatigue monitoring and mitigation systems.
    • Established systems for hazard identification and risk assessment were incorporated.

    Conclusions:

    • The presented method has been successfully used in other safety cases.
    • Evidence requirements for safety cases should adapt to the perceived risk level.
    • Experience with fatigue risk management systems should inform evolving safety case evidence.