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Updated: Feb 27, 2026

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti ratti Infection
Published on: January 17, 2025
Novel Findings in HIV, Immune Reconstitution Disease and Strongyloides stercoralis Infection
Roberto G Aru1, Benjamin M Chilcutt2, Saira Butt3
1Department of Medicine, Division of Internal Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Abstract:
We report the successful treatment of an HIV-infected patient with progressive strongyloidiasis as a component of immune reconstitution disease and a review of the literature on this topic. In our experience, pre- and post-antiretroviral therapy intestinal biopsies support a novel mechanism of immune reconstitution disease to Strongyloides stercoralis. We conclude that extended, dual antihelminthic therapy and temporary discontinuation of antiretroviral therapy may be effective in similar patients.
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