Related Experiment Video
Updated: Feb 27, 2026
07:41
Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction
Published on: June 7, 2011
53.3K
Clinical Study of 27 Patients with Medial Medullary Infarction.
Takayoshi Akimoto1, Katsuhiko Ogawa1, Akihiko Morita1
1Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
Summary
Medial medullary infarction (MMI) is a rare stroke. Motor weakness and sensory loss are common, with larger infarcts correlating to more severe sensory deficits. Facial and tongue weakness are typically supranuclear.
Area of Science:
- Neurology
- Neuroscience
- Internal Medicine
Background:
- Medial medullary infarction (MMI) is an uncommon type of ischemic stroke.
- Neurological findings in MMI vary across studies.
Purpose of the Study:
- To analyze the frequency and characteristics of neurological findings in patients with medial medullary infarction.
- To investigate the relationship between infarct size and neurological deficits in MMI.
Main Methods:
- Retrospective analysis of medical records of patients diagnosed with MMI via MRI.
- Evaluation of neurological findings, infarct locations, and etiologies in a cohort of MMI patients.
Main Results:
- Out of 2727 ischemic stroke patients, 27 had MMI, with large-artery atherosclerosis being the most common cause.
- Motor weakness of extremities was the most frequent neurological finding.
- Diminished superficial and vibratory sensations were common, especially in larger MMI cases. Supranuclear facial weakness and lingual palsy were more prevalent than infranuclear types.
Conclusions:
- Motor weakness and sensory disturbances are key features of MMI, with larger infarcts leading to more pronounced sensory loss.
- Supranuclear facial weakness and lingual palsy are more characteristic of MMI than infranuclear types.
