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Differentiation of Human Pluripotent Stem Cells Into Pancreatic Beta-Cell Precursors in a 2D Culture System
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Pathways governing development of stem cell-derived pancreatic β cells: lessons from embryogenesis

Sara Al-Khawaga1, Bushra Memon1, Alexandra E Butler2

  • 1Diabetes Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, Education City, Doha, Qatar.

Biological Reviews of the Cambridge Philosophical Society
|June 24, 2017
PubMed
Summary

Human pluripotent stem cells (hPSCs) are key to understanding diabetes and developing new therapies. Research explores how signaling pathways guide pancreatic beta cell development from hPSCs for diabetes treatment and modeling.

Keywords:
developmentgeneshESCshiPSCsinsulin-secreting cellspancreatic precursorstranscription factors

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