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Two new prenylflavonoids from Morus alba.

Li Gao¹, Yuan-Dong Li¹, Bao-Kun Zhu¹

¹a Technical Center of China Tobacco Yunnan Industrial Co., Ltd. , Kunming 650231 , China.

Journal of Asian Natural Products Research

|June 24, 2017

Summary

Researchers identified two novel prenylflavonoids, morusalbols A and B, from the Morus alba plant. Their structures were determined using detailed spectroscopic analysis, expanding knowledge of plant-derived compounds.

Keywords:

Moraceae Morus alba morusalbol A morusalbol B prenylflavonoid

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Area of Science:

Phytochemistry
Natural Product Chemistry
Organic Chemistry

Background:

Morus alba (mulberry) is a plant species known for its diverse secondary metabolites.
Flavonoids, a class of natural products, exhibit a wide range of biological activities.
Prenylated flavonoids represent a subclass with unique structural features and potential pharmacological properties.

Purpose of the Study:

To isolate and characterize novel prenylflavonoids from Morus alba.
To elucidate the chemical structures of newly discovered compounds.
To contribute to the understanding of the phytochemical diversity of Morus alba.

Main Methods:

Extraction of compounds from the branches and leaves of Morus alba.
Isolation of prenylflavonoids using chromatographic techniques.
Structure elucidation employing extensive spectroscopic data analysis (e.g., NMR, MS).

Main Results:

Two new prenylflavonoids, designated morusalbols A (1) and B (2), were successfully isolated.
Three known compounds, kuwanon C (3), morusin (4), and morusinol (5), were also identified.
The chemical structures of morusalbols A and B were definitively determined through comprehensive spectroscopic analysis.

Conclusions:

The study successfully identified and characterized two new prenylflavonoids from Morus alba.
The findings enhance the known phytochemical profile of Morus alba.
This research provides valuable chemical entities for further investigation into their biological activities.