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Numerical analysis of time-dependent inhibition kinetics: comparison between rat liver microsomes and rat hepatocyte

Chuong Pham1, Swati Nagar1, Ken Korzekwa1

  • 1Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USA.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|June 24, 2017
PubMed

Keywords:
Cytochrome P450hepatocytesmechanism-based inhibitionmicrosomestime-dependent inhibition

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