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Passive smoking and mortality from aortic dissection or aneurysm.

Tomomi Kihara1, Kazumasa Yamagishi2, Hiroyasu Iso3

  • 1Department of Public Health Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan; Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Atherosclerosis
|June 24, 2017
PubMed
Summary

Passive smoking, especially outside the home, significantly increases the risk of death from aortic dissection or aneurysm. This finding highlights the dangers of secondhand smoke exposure for cardiovascular health.

Keywords:
AortaCardiovascular diseaseEnvironmental tobacco smokeEpidemiologySecondhand smoke

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Area of Science:

  • Cardiovascular Epidemiology
  • Public Health Research
  • Environmental Health

Background:

  • Limited evidence exists on the link between passive smoking and aortic dissection or aneurysm.
  • Investigating passive smoking's role in aortic disease mortality is crucial for public health.

Purpose of the Study:

  • To determine if passive smoking exposure elevates the risk of death from aortic dissection or aneurysm.
  • To quantify the association between different levels of passive smoke exposure and aortic disease mortality.

Main Methods:

  • Utilized data from the Japan Collaborative Cohort (JACC) Study (1988-2009).
  • Analyzed 48,677 never-smokers, categorizing passive smoke exposure (out of home, at home, combined).
  • Examined mortality from aortic dissection and aneurysm as the primary endpoint.

Main Results:

  • High passive smoking exposure out of home showed a hazard ratio of 2.45 (1.02-5.88) for aortic dissection or aneurysm mortality.
  • Combined out-of-home and at-home passive smoking exposure (high group) had a hazard ratio of 2.35 (1.09-5.09).
  • Current smokers exhibited significantly higher risks compared to the low passive-smoking group.

Conclusions:

  • Passive smoking outside the home is associated with increased mortality from aortic dissection or aneurysm.
  • Combined passive smoking exposure (both at home and out of home) also increases aortic disease mortality risk.
  • Findings underscore the importance of reducing secondhand smoke exposure to prevent fatal aortic events.