Related Experiment Video
Updated: Feb 27, 2026

Characterization of Neuromuscular Junctions in Mice by Combined Confocal and Super-Resolution Microscopy
Published on: December 8, 2021
Perturbation to Cholesterol at the Neuromuscular Junction Confers Botulinum Neurotoxin A Sensitivity to Neonatal Mice
Baskaran Thyagarajan1, Joseph G Potian2, Joseph J McArdle2
1School of Pharmacy, College of Health Sciences University of Wyoming, Laramie, Wyoming 82071.
Abstract:
Botulinum neurotoxin A (BoNT/A) cleaves SNAP25 at the motor nerve terminals and inhibits stimulus evoked acetylcholine release. This causes skeletal muscle paralysis. However, younger neonatal mice (
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