Related Experiment Video
Updated: Feb 27, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Factors predicting self-reported medication low adherence in a large sample of adults in the US general population: a
Michael Feehan1,2, Margaux A Morrison2, Casey Tak1
1The Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Objectives:
The study objective was to determine the level and correlates of self-reported medication low adherence in the US general population.
Setting:
A 30 min cross-sectional online survey was conducted with a national sample of adults.
Participants:
9202 adults (aged 18+) who had filled at least three or more prescriptions at a community pharmacy in the past 12 months.
Primary And Secondary Outcome Measures:
Self-reported medication adherence was measured with the 8-item Morisky Medication Adherence Scale.
Results:
Low adherence was reported by 42.0%, 29.4% had medium adherence and 28.6% had high adherence. Low adherence was significantly associated with: lower age, being of Hispanic origin or African-American, having difficulty with healthcare, medication or transportation costs, needing the support of others to access primary care, health limiting activity, using multiple providers, infrequent visits to primary care providers and visiting an emergency department >3 times in last 12 months.
Conclusions:
A very high level of low medication adherence is seen in the general population, particularly for ethnic minorities, those who use multiple healthcare providers and those who experience barriers to access for regular primary care. As clinical, patient education and counselling, and healthcare policy initiatives are directed to tracking the problem of low medication adherence, these should be priority populations for research and interventions.
More Related Videos
05:59Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
Published on: March 7, 2019
05:40The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
Related Concept Videos
Drug Toxicity: Risk factors
Drug Dosing: Geriatric Patients
Factors Affecting Drug Response: Overview
Factors Influencing Drug Absorption: Disease States and Pharmacology
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Factors Affecting Protein-Drug Binding: Patient-Related Factors
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Dosage Regimens: Partial Pharmacokinetic Parameters