Diagnosis and treatment for hyperuricaemia and gout: a protocol for a systematic review of clinical practice
Qianrui Li1, Xiaodan Li2, Joey Sum-Wing Kwong3,4,5
1Department of Endocrinology and Metabolism 610041, West China Hospital, Sichuan University, Chengdu, China.
Insights
This systematic review appraises clinical practice guidelines for gout and hyperuricaemia. It aims to clarify inconsistent recommendations and assess guideline quality for better patient care.
Area of Science:
- Rheumatology
- Clinical Practice Guidelines
- Systematic Review
Background:
- Gout and hyperuricaemia are significant health concerns with numerous existing guidelines.
- Current guidelines present inconsistent recommendations and have variable quality profiles.
Purpose of the Study:
- To systematically appraise clinical practice guidelines and consensus statements for gout and hyperuricaemia diagnosis and treatment.
- To summarize recommendations from these documents.
Main Methods:
- Comprehensive literature search of PubMed, EMBASE, and guideline databases.
- Inclusion of Google and Google Scholar for broader document identification.
- Quality assessment using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument.
- Manual extraction of clinical practice recommendations.
Main Results:
- (Results not yet available as this is a protocol.)
Conclusions:
- (Conclusions not yet available as this is a protocol.)
Introduction:
Gout and hyperuricaemia are major health issues and relevant guidance documents have been released by a variety of national and international organisations. However, these documents contain inconsistent recommendations with unclear quality profiles. We aim to conduct a systematic appraisal of the clinical practice guidelines and consensus statements pertaining to the diagnosis and treatment for hyperuricaemia and gout, and to summarise recommendations.
Methods:
We will search PubMed, EMBASE and guideline databases to identify published clinical practice guidelines and consensus statements. We will search Google and Google Scholar for additional potentially eligible documents. The quality of included guidelines and consensus statements will be assessed using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument and be presented as scores. We will also manually extract recommendations for clinical practice from all included documents.
Ethics And Dissemination:
The results of this systematic review will be disseminated through relevant conferences and peer-reviewed journals.
Protocol Registration Number:
PROSPERO CRD42016046104.
Related Concept Videos
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Urinary Tract Calculi V: Nursing Management
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Nephrotic Syndrome II : Assessment and Medical Management
![Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F61682.jpg&w=3840&q=50)