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Updated: Feb 27, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Oncocytic adrenocortical carcinoma: a rare adrenal tumor subtype
Emma Sumner1, Behram Cenk Acar, Matthew R Acker
1Department of Urology, Saint John Regional Hospital, Saint John, New Brunswick, Canada.
Abstract:
Oncocytic tumors arising from the adrenal gland are rare. Oncocytic adrenal neoplasms (OAN) may mimic adrenocortical carcinoma (ACC) at presentation, and can only be definitively diagnosed histologically. Most OANs are benign, and carry a favorable prognosis. We report on an 83-year-old female who, while being investigated for anemia and weight loss, was found to have a 23 cm adrenal mass concerning for ACC. Adrenalectomy and histopathology confirmed a malignant OAN, based on the Lin-Weiss-Bisceglia criteria. We report on the largest non-functional, malignant OAN cited in the literature to date. OAN's, though rare, can be considered in the differential diagnosis of large adrenal tumors.
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