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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
Published on: August 23, 2016
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An update on Zika virus infection
David Baud1, Duane J Gubler2, Bruno Schaub3
1Materno-fetal and Obstetrics Research Unit, Obstetric Service, Department "Femme-Mère-Enfant", University Hospital, Lausanne, Switzerland.
Lancet (London, England)
|June 26, 2017
Summary
The Zika virus epidemic, beginning in 2007, caused severe neurological complications and spread globally. This review covers updates and knowledge gaps regarding Zika virus as of early 2017.
Area of Science:
- Epidemiology
- Virology
- Public Health
Background:
- Zika virus emerged in 2007, with major epidemics in the Pacific and Brazil.
- The virus caused severe neurological complications, including microcephaly, and non-vector-borne transmission.
- Global health emergencies were declared due to Zika virus outbreaks and associated neurological disorders.
Purpose of the Study:
- To review important updates on Zika virus epidemiology and transmission.
- To identify current knowledge gaps regarding Zika virus.
- To provide a comprehensive overview of Zika virus as of early 2017.
Main Methods:
- Literature review of Zika virus outbreaks and research.
- Analysis of epidemic history and transmission patterns.
- Synthesis of data on severe neurological complications.
Main Results:
- Zika virus spread globally, causing outbreaks in the Americas, Pacific, Africa, and Asia.
- Confirmed non-vector-borne transmission and established causal link to severe neurological disorders.
- Identified clusters of microcephaly and other neurological issues in affected populations.
Conclusions:
- Zika virus poses a significant global public health threat.
- Further research is needed to address knowledge gaps in Zika virus prevention and treatment.
- Continued surveillance and preparedness are crucial for managing Zika virus outbreaks.
