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Updated: Aug 11, 2026

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
Published on: February 26, 2014
[Several remarks apropos of quantitative psychopathology]
Abstract:
There is no contradiction between rating scales and clinical judgment: the former represent only a codification of the latter. There is no contradiction either between clinical judgment and statistical judgment. Rating scales are elaborated with hopes of quantifying symptomatology and its change under treatment. In the field of comprehensive scales, let us mention the AMDP, the BPRS/BPHF, the IMPS and the PSE. Among depression scales, the HAMD is being superseded by the MADRS; our Department has also made an extensive use of the Overall Depression scale. Mania scales insufficiently discriminate between manic mood and agitation. As regards anxiety scales, the HAMA is an excellent one. In the field of somatic scales, we have developed the CHESS, which appears promising. In the field of diagnostic typology, the recent criteria by Pull might bring better results that previous research. Adequate scales are missing in mania, in the distinction between the psychostimulant and the antidepressant effects, in the field of vigilance-attention-memory and in the measurement of psychotherapeutic change.
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