Mapping Sri Lankan EQ-5D-3L to EQ-5D-5L Value Sets

Area of Science:

• Health Economics
• Psychometrics
• Outcome Measurement

Background:

• Quality-adjusted life-years (QALYs) are standard in health economic evaluations.
• The EQ-5D-5L classification system offers greater sensitivity than the EQ-5D-3L for specific conditions.
• A country-specific value set is essential for accurate health economic assessments.

Purpose of the Study:

• To estimate the Sri Lankan value set for the EQ-5D-5L health states.
• To utilize a crosswalk methodology for generating the value set.
• To provide a crucial resource for health economic evaluations in Sri Lanka.

Main Methods:

• Employed the EuroQoL group's crosswalk method to map EQ-5D-3L to EQ-5D-5L health states.
• Generated an interim Sri Lankan EQ-5D-5L value set based on the existing Sri Lankan EQ-5D-3L value set (n=780, time trade-off method).
• Compared the derived Sri Lankan EQ-5D-5L values with those from other countries.

Main Results:

• The Sri Lankan EQ-5D-5L utility values ranged from -0.73 (worst state) to 0.85 (near-perfect health).
• Mean utility values in Sri Lanka (0.07) were lower than in the UK (0.4) and Japan (0.45).
• Median values showed Thailand (0.21) and Sri Lanka (0.14) were closer than the UK (0.41) or Japan (0.45).

Conclusions:

• Successfully produced an interim Sri Lankan EQ-5D-5L value set using the crosswalk methodology.
• This represents the first and only EQ-5D-5L value set currently available for the South Asian region.
• The generated value set will support more accurate health economic evaluations in Sri Lanka and potentially neighboring countries.