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Updated: Feb 27, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Utility of adjunctive modalities in Coronary chronic total occlusion intervention
Hemal Bhatt1, Sean Janzer1, Jon C George1
1Division of Cardiovascular Disease, Department of Internal Medicine, Einstein Medical Center, Philadelphia, PA 19141, USA.
Insights
Percutaneous coronary intervention for chronic total occlusion (CTO PCI) is complex. Adjunctive tools like intravascular imaging and atherectomy may improve CTO PCI success rates and lesion assessment.
Area of Science:
- Interventional Cardiology
- Cardiovascular Research
Background:
- Coronary chronic total occlusion (CTO) interventions present significant technical challenges.
- CTO percutaneous coronary intervention (PCI) has lower attempt and success rates compared to standard PCI due to complexity and risks.
Purpose of the Study:
- To review the current literature on adjunctive tools used in CTO intervention.
- To assess the utility and efficacy of these tools in improving CTO PCI outcomes.
Main Methods:
- Review of current scientific literature on CTO intervention.
- Analysis of the role of specific adjunctive modalities.
Main Results:
- Adjunctive tools including intravascular ultrasound, optical coherence tomography, rotational atherectomy, orbital atherectomy, excimer laser coronary atherectomy, and percutaneous left ventricular assist devices are discussed.
- These tools show potential for enhancing CTO PCI success rates and improving hemodynamic assessment.
Conclusions:
- Adjunctive modalities are crucial for addressing the complexities of CTO PCI.
- Further research and application of these tools can optimize patient outcomes in CTO intervention.
Abstract:
Coronary chronic total occlusion (CTO) intervention remains one of the most challenging domains in interventional cardiology. Due to the technical challenges involved and potential procedural complications, CTO percutaneous coronary intervention (PCI) attempt and success rates remain less than standard PCI. However, the use of several adjunctive tools such as intravascular ultrasound, optical coherence tomography, rotational atherectomy, orbital atherectomy, excimer laser coronary atherectomy and percutaneous left ventricular assist device may contribute to improved CTO PCI success rates or provide better hemodynamic assessment of CTO lesion (i.e., using fractional flow reserve). In this review we present the current literature describing the utility and efficacy of these adjunctive modalities in CTO intervention.
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