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Updated: Feb 27, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

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Applying Structure-Based Drug Design Approaches to Allosteric Modulators of GPCRs

Miles Congreve1, Christine Oswald1, Fiona H Marshall1

  • 1Heptares Therapeutics Ltd, Biopark, Welwyn Garden City, UK.

Trends in Pharmacological Sciences
|June 27, 2017
PubMed

Keywords:
G protein-coupled receptorX-ray crystallographyallosteric modulatorstructure-based drug design

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