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Updated: Feb 27, 2026

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
Published on: April 3, 2017
Disease- or Storage-Associated Structural Modifications Are Unlikely to Explain HDL Pro-inflammatory Effects on
Emiel P C van der Vorst1, Kosta Theodorou2, Erik A L Biessen3
1Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, 6211 LK Maastricht, the Netherlands; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University, 80539 Munich, Germany.
Abstract:
Van der Vorst et al. underscore the relevance of HDL quality control, considering HDL source and processing, but argue that disease- or storage-associated structural modifications of HDL cannot explain the observed pro-inflammatory effects on macrophages. Discrepancies between reported effects of HDL in macrophages are probably related to methodological differences.
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