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Related Experiment Video

Updated: Feb 27, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
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Accommodating Intraocular Lenses.

Jay S Pepose1,2, Joshua Burke1, Mujtaba Qazi1,2

  • 1Pepose Vision Institute, Chesterfield, Missouri.

Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|June 27, 2017
PubMed
Summary
This summary is machine-generated.

Developing accommodating intraocular lenses (IOLs) to restore vision is crucial due to the rising prevalence of presbyopia. This review explores advancements in IOL designs aimed at achieving greater accommodative amplitude for refractive surgery.

Keywords:
clinical outcomesintraocular lenslens design

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Materials Science

Background:

  • Presbyopia, an age-related loss of focusing ability, affects a growing global population.
  • Current intraocular lens (IOL) technology often fails to fully restore accommodative amplitude.
  • The development of advanced IOLs is a key goal in refractive surgery.

Purpose of the Study:

  • To review the progress in accommodating intraocular lens (IOL) designs.
  • To analyze the clinical outcomes and complications associated with implanted IOLs.
  • To identify remaining challenges in IOL technology.

Main Methods:

  • Review of scientific literature on accommodating IOLs.
  • Analysis of different IOL designs: positional, shape-changing, and refractive index modulation.
  • Evaluation of clinical data and reported complications.

Main Results:

  • Multiple IOL designs (single/dual optic) have been developed using various strategies.
  • Clinical outcomes and complications vary significantly across different IOL designs.
  • No single IOL design has yet achieved the 'holy grail' of expansive accommodative amplitude.

Conclusions:

  • Significant advancements have been made in accommodating IOL technology.
  • Further innovation is needed to overcome challenges and achieve full restoration of accommodation.
  • Continued research into IOL design is essential for improving refractive surgery outcomes.