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Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision
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Endodontic microleakage studies: correlation among different methods, clinical relevance, and potential laboratory

Farnaz Jafari1, Saeed Rahimi2, Shahriar Shahi2

  • 1Department of Endodontics, Dental School, Tabriz Branch, Islamic Azad University, Tabriz, Iran.

Minerva Stomatologica
|June 27, 2017
PubMed
Summary

Ensuring a tight seal in endodontically treated root canals is crucial. This review highlights that while microleakage studies in endodontics have potential laboratory errors, they remain valuable for assessing sealing ability.

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Area of Science:

  • Endodontics
  • Dental Materials Science

Background:

  • Achieving a hermetic seal in endodontically treated root canals is paramount for long-term success.
  • Clinical and laboratory investigations are vital for evaluating the sealing efficacy of endodontic materials.
  • This review critically examines the correlation between various microleakage study techniques and potential laboratory errors in endodontics.

Purpose of the Study:

  • To evaluate the correlation between different microleakage study techniques in endodontics.
  • To identify and analyze potential laboratory errors associated with these techniques.
  • To provide recommendations for improving the reliability of microleakage studies.

Main Methods:

  • A systematic literature search was conducted across major scientific databases including Medline, Biosis, Cochrane, Embase, Google Scholar, and Web of Science.
  • Reference lists of relevant articles were also thoroughly searched without language restrictions.
  • Titles and abstracts were independently reviewed by two researchers to ensure comprehensive data extraction.

Main Results:

  • Microleakage studies can be improved with larger sample sizes and well-designed control groups.
  • Recommendations include additional reliability assessments, such as glucose reactivity tests, antimicrobial activity evaluations, and in situ FISH for bacterial leakage.
  • Utilizing multiple testing methods per material and incorporating long-term animal studies with histological/radiographic analysis, alongside controlled human clinical trials, is advised.

Conclusions:

  • Microleakage studies, encompassing animal models, clinical trials, and laboratory tests, are essential in endodontics.
  • Despite inherent potential for laboratory errors, these studies provide invaluable data for assessing the sealing ability of endodontic materials.