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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

7.8K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Related Experiment Video

Updated: Feb 27, 2026

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner
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Quantitative positron emission tomography in brain research.

Kerstin Heurling1, Antoine Leuzy2, My Jonasson3

  • 1Wallenberg Centre for Molecular and Translational Medicine and the Department of Psychiatry and Neurochemistry, University of Gothenburg, Sweden; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Brain Research
|June 28, 2017
PubMed
Summary

Positron emission tomography (PET) offers unique insights into brain function and disease. This review covers PET fundamentals, quantitative methods, and applications in neuroscience, neurology, and psychiatry.

Keywords:
BrainDiagnosticsImaging biomarkersMolecular imagingPositron emission tomography

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Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Positron emission tomography (PET) use in brain research has grown significantly over the last 20 years.
  • PET imaging provides unique in vivo insights into physiological and pathological brain processes.

Purpose of the Study:

  • To introduce the fundamentals and quantitative methods of PET.
  • To outline diverse applications of PET in brain research, including basic science and clinical diagnostics.

Main Methods:

  • Introduction to the principles of Positron Emission Tomography (PET).
  • Explanation of methods for quantitative estimation of parameters in PET studies.
  • Overview of application areas.

Main Results:

  • PET is a valuable tool for studying brain function and diseases.
  • Applications span basic neuroscience, neurology, psychiatry, and diagnostics for neurodegenerative disorders.

Conclusions:

  • PET is an increasingly important technique in brain research.
  • The article aims to inform readers about PET basics and inspire its adoption in their research.