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Optic perineuritis: a retrospective case series
Olle Bergman1, Tommy Andersson1, Madeleine Zetterberg1,2
1Department of Ophthalmology, Sahlgrenska University Hospital.
International Medical Case Reports Journal
|June 28, 2017
Summary
Optic perineuritis (OPN) is a rare optic nerve inflammation causing vision loss. This case series highlights corticosteroid treatment effectiveness for OPN patients with severe symptoms.
Area of Science:
- Ophthalmology
- Neurology
- Inflammatory Disorders
Background:
- Optic perineuritis (OPN) is a rare inflammatory condition affecting the optic nerve sheath.
- It can manifest as an isolated idiopathic condition or be associated with systemic disorders.
- OPN characteristically presents with visual loss.
Purpose of the Study:
- To aid clinicians in the investigation and management of optic perineuritis.
- To describe the presentation, clinical findings, and treatment outcomes of OPN patients.
Main Methods:
- A retrospective case series was conducted.
- Medical records of seven OPN patients from Sahlgrenska University Hospital, Sweden, were reviewed.
- Patient demographics, clinical presentation, and treatment regimens were analyzed.
Main Results:
- Seven patients (3 male, 4 female) aged 26-64 years were included.
- Cases encompassed both idiopathic OPN and those associated with underlying disorders.
- Five patients received corticosteroid treatment, showing positive outcomes in severe cases.
Conclusions:
- High-dose corticosteroid therapy is crucial for managing severely affected OPN patients.
- Effective investigation and management strategies for OPN are essential.
- Further research into OPN's underlying causes and optimal treatment is warranted.
Keywords:
corticosteroidsglucocorticoidsidiopathicinflammationmagnetic resonance imagingprednisonevision
