Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lymph node mapping-based optimal bowel-resection margin and central radicality in colon cancer surgery: an international, prospective, observational cohort study.

ESMO gastrointestinal oncology·2026
Same author

Defining Standard Data Reporting in Pelvic Exenterations for Non-Rectal Cancers: A Systematic Review of Current Data Reporting.

Cancers·2025
Same author

Survival benefit of adjuvant chemotherapy in elderly patients with UICC stage III colon carcinoma: A 20-year population-based German cohort study.

European journal of cancer (Oxford, England : 1990)·2025
Same author

Treatment-Free Remission Outcomes in a BCR::ABL1 Digital PCR Selected Clinical Cohort of CML Patients.

European journal of haematology·2025
Same author

The impact of neoadjuvant therapy in patients with left-sided resectable pancreatic cancer: an international multicenter study.

Annals of oncology : official journal of the European Society for Medical Oncology·2025
Same author

The management of retrorectal tumors - a single-center analysis of 21 cases and overview of the literature.

Langenbeck's archives of surgery·2024
Same journal

[S3 Guideline "Adult soft tissue sarcomas"].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Synopsis-S3 guidelines pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Laparoscopic sentinel node navigation surgery in gastric cancer to reduce surgical radicality].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Future concepts for neoadjuvant and adjuvant treatment of (resectable) pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[ASCO guidelines for the treatment of stage III NSCLC part 4: indications for adjuvant therapy].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Surgical treatment of pancreatic cancer-What is new?]

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
10:38

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

Published on: February 1, 2020

8.0K

[R1 resection for pancreatic carcinoma].

G F Weber1, S Kersting2, F Haller3

  • 1Chirurgische Klinik, Universitätsklinikum Erlangen, Krankenhausstraße 12, 91054, Erlangen, Deutschland. georg.weber@uk-erlangen.de.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|June 28, 2017
PubMed
Summary
This summary is machine-generated.

Achieving negative resection margins (R0) in pancreatic cancer surgery is crucial for survival. While R1 margins impact outcomes, re-resection and new neoadjuvant/adjuvant therapies can improve results for pancreatic ductal adenocarcinoma (PDAC).

Keywords:
Arterial vascular resectionFollow-up resectionMultimodal and surgical treatmentStandardized pathological examinationSurvival

More Related Videos

Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer
12:07

Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer

Published on: November 18, 2022

4.6K
An Orthotopic Resectional Mouse Model of Pancreatic Cancer
07:17

An Orthotopic Resectional Mouse Model of Pancreatic Cancer

Published on: September 24, 2020

12.7K

Related Experiment Videos

Last Updated: Feb 27, 2026

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
10:38

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

Published on: February 1, 2020

8.0K
Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer
12:07

Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer

Published on: November 18, 2022

4.6K
An Orthotopic Resectional Mouse Model of Pancreatic Cancer
07:17

An Orthotopic Resectional Mouse Model of Pancreatic Cancer

Published on: September 24, 2020

12.7K

Area of Science:

  • Surgical Oncology
  • Gastroenterology
  • Cancer Research

Background:

  • Pancreatic ductal adenocarcinoma (PDAC) surgery offers the only potential cure.
  • Negative (R0) resection margins are critical but not always achievable.

Purpose of the Study:

  • To evaluate the impact of R1 resection margins on survival.
  • To explore treatment options for intraoperative and postoperative R1 margins in PDAC.

Main Methods:

  • Analysis of surgical outcomes for R1 resection margins.
  • Review of re-resection techniques and multimodal treatment strategies.
  • Assessment of neoadjuvant and adjuvant therapy impacts on PDAC resectability and outcomes.

Main Results:

  • Intraoperative R1 margins may be addressed with re-resection, including complex vascular or multi-organ procedures.
  • Advanced neoadjuvant and adjuvant treatments enhance PDAC resectability and improve outcomes for R0/R1 resections.
  • Arterial resections and additional organ resections are feasible in select cases.

Conclusions:

  • R0 resection is the primary surgical goal for PDAC due to the poor prognosis associated with R1 resections.
  • Multimodal approaches and re-resection strategies can improve outcomes for patients with R1 margins.