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Mouse Models Of Helicobacter Infection And Gastric Pathologies
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Mouse Models Of Helicobacter Infection And Gastric Pathologies

Published on: October 18, 2018

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Zoonotic potential of Helicobacter spp

Irena Mladenova-Hristova1, Olga Grekova1, Ami Patel2

  • 1Department of Hygiene, Epidemiology and Inf. Diseases, Medical Faculty, Trakia University, Stara Zagora, Bulgaria.

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
|June 29, 2017
PubMed

Insights

The Helicobacter genus includes over 35 species, with Helicobacter pylori impacting human health. Studying these gut bacteria and their diseases reveals pathogenic mechanisms and zoonotic transmission potential.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Zoonoses

Background:

  • The genus Helicobacter comprises over 35 bacterial species.
  • Helicobacter pylori is a significant human pathogen.
  • Understanding Helicobacter spp. interactions with hosts is crucial.

Purpose of the Study:

  • To explore the relationships among Helicobacter species colonizing animal and human guts.
  • To investigate the pathogenic mechanisms of Helicobacter infections.
  • To highlight the importance of studying zoonotic transmission and epidemiology of emerging Helicobacter pathogens.

Main Methods:

  • Comparative analysis of Helicobacter species.
  • Infection studies in host models.
  • Epidemiological investigations.

Main Results:

  • Identification of diverse Helicobacter species and their hosts.
  • Elucidation of bacterial factors contributing to pathogenesis.
  • Evidence for potential zoonotic transmission routes.

Conclusions:

  • Helicobacter spp. represent a diverse group of emerging pathogens with significant host impact.
  • Further research into their epidemiology and zoonotic potential is warranted.
  • Understanding host-pathogen interactions is key to managing associated diseases.
Keywords:
Chronic gastritisHelicobacter pyloriHelicobacter spp.Peptic ulcer diseaseZoonosis

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