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COPASI and its applications in biotechnology.
Frank T Bergmann1, Stefan Hoops2, Brian Klahn2
1BioQuant/COS, Heidelberg University, Heidelberg, Germany.
Journal of Biotechnology
|June 29, 2017
Summary
COPASI is a versatile, open-source software for creating, simulating, and analyzing kinetic models in biosciences. Its user-friendly interface and scripting capabilities contribute to its widespread adoption in computational biology and biotechnology.
Area of Science:
- Computational biology and systems biology
- Biotechnology and biochemical engineering
Background:
- Computational modeling is crucial for understanding complex biological systems.
- Kinetic models are essential for simulating dynamic biological processes.
Purpose of the Study:
- To introduce the COPASI software package.
- To describe its capabilities for kinetic model creation, modification, simulation, and analysis.
- To highlight its applications in biotechnology.
Main Methods:
- Utilizes a user-friendly graphical interface.
- Supports command-line and scripting language control.
- Facilitates the creation and analysis of biochemical reaction networks.
Main Results:
- COPASI is open-source and available on major platforms.
- It offers a comprehensive suite of tools for kinetic modeling.
- Demonstrates wide acceptance due to its flexibility and accessibility.
Conclusions:
- COPASI is a powerful and accessible tool for computational modeling in biosciences.
- Its features support diverse applications, particularly in biotechnology.
- The software's design promotes broad adoption and utility.
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