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Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
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Peri-operative blood management.

Alex Eeles1, Ravishankar Rao Baikady1

  • 1Department of Anaesthesia The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.

Indian Journal of Anaesthesia
|June 29, 2017
PubMed
Summary
This summary is machine-generated.

Patient blood management (PBM) optimizes surgical patient outcomes by addressing anemia and reducing transfusions. This evidence-based approach improves patient health and offers economic benefits.

Keywords:
Anaemiairon deficiencypatient blood managementperi-operative

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Area of Science:

  • Perioperative Medicine
  • Transfusion Medicine
  • Surgical Outcomes

Background:

  • Anemia and allogeneic blood transfusions are linked to adverse outcomes in surgical patients.
  • Patient Blood Management (PBM) is an evidence-based strategy to mitigate these risks.
  • PBM encompasses pre-operative, intra-operative, and post-operative care phases.

Purpose of the Study:

  • To review recent evidence-based updates on PBM in the perioperative setting.
  • To highlight PBM's role in optimizing anemia and managing bleeding.
  • To emphasize PBM's contribution to improving patient outcomes.

Main Methods:

  • Comprehensive literature review of original research, guidelines, and consensus documents.
  • Extensive search of PubMed and Medline databases.
  • Analysis of PBM strategies across the perioperative continuum.

Main Results:

  • PBM promotes a restrictive transfusion approach and alternatives to maximize efficacy and minimize risks.
  • Pre-operative anemia correction is crucial, potentially delaying elective surgery.
  • Intra-operative PBM involves collaboration, tranexamic acid, hemostasis, cell salvage, and point-of-care testing for tailored transfusion.

Conclusions:

  • PBM is essential for optimizing surgical patients, addressing anemia, and managing bleeding.
  • Effective PBM implementation leads to improved individual health outcomes.
  • PBM strategies provide significant economic benefits alongside clinical advantages.