Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Liver function disorders and damage in critically ill intensive care patients].

G Kleinberger

    Leber, Magen, Darm
    |September 1, 1985
    PubMed
    Summary

    Critically ill patients often experience liver dysfunction, even without primary liver disease. This study highlights the need for regular liver function tests in intensive care settings to improve patient prognosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Inadvertent duplicate publication: Severe poisoning with slow release theophylline.

    British medical journal (Clinical research ed.)·2010
    Same author

    Influence of a novel amino acid solution (enriched with the dipeptide glycyl-tyrosine) on plasma amino acid concentration of patients with acute renal failure.

    Clinical nutrition (Edinburgh, Scotland)·2006
    Same author

    Amino acid kinetics in patients with sepsis.

    The American journal of clinical nutrition·2001
    Same author

    Hypophosphatemia in patients with chronic renal failure during total parenteral nutrition.

    JPEN. Journal of parenteral and enteral nutrition·1999
    Same author

    Energy metabolism in patients with acute and chronic liver disease.

    Hepatology (Baltimore, Md.)·1990
    Same author

    Assessment of oxygen-consumption by use of reverse Fick-principle and indirect calorimetry in critically ill patients.

    Clinical nutrition (Edinburgh, Scotland)·1989

    Area of Science:

    • Critical Care Medicine
    • Hepatology
    • Organ Failure

    Context:

    • Critically ill patients frequently develop multi-organ dysfunction, with a disproportionate focus on cardio-pulmonary and renal systems.
    • Liver function is often overlooked in intensive care despite its critical role in patient outcomes.
    • This retrospective study examined 100 critically ill patients with elevated serum bilirubin levels but no primary liver disease.

    Purpose:

    • To investigate the prevalence and characteristics of liver dysfunction in critically ill patients without primary liver disease.
    • To identify potential correlations between various liver function parameters in this patient cohort.
    • To underscore the importance of comprehensive liver function monitoring in intensive care.

    Summary:

    • Severe infection was the primary cause in 64% of patients, with high rates of septicemia, post-operative/traumatic status, gastrointestinal complications, myocardial failure, shock, hematological, lung, and renal failure.
    • Despite significant pathological findings, only serum glutamate-pyruvate transaminase (SGPT) and serum lactate dehydrogenase (SLDH) showed a statistically significant correlation.
    • Liver involvement is common and significant in critically ill patients, necessitating thorough and repeated liver function assessments.

    Impact:

    • Highlights the underappreciated role of liver dysfunction in critically ill patients.
    • Emphasizes the need for routine and comprehensive liver function testing in intensive care units.
    • Suggests that improved monitoring of liver function may lead to better patient prognoses and outcomes.

    Related Experiment Videos