Related Experiment Video
Updated: Feb 27, 2026

07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
896
Paradoxical embolism: A report of 2 cases
Jie Geng1, Hong-Yan Tian, Yan-Min Zhang
1Department of Peripheral Vascular Disease, the First Affiliated Hospital of Xi'an Jiaotong University Section of Pediatric Cardiology, Heart Center, Northwest Women's and Children's Hospital Department of Breast Cancer, Shaanxi Provincial Tumor Hospital, Xi'an, Shaanxi, PR China.
Medicine
|June 29, 2017
Summary
Paradoxical embolism (PDE), a condition where blood clots travel from veins to arteries, can present with diverse symptoms. Early diagnosis through careful examination is key for successful treatment and patient recovery.
Area of Science:
- Cardiology
- Neurology
Background:
- Paradoxical embolism (PDE) involves venous thrombi bypassing pulmonary circulation to enter arterial pathways via arteriovenous shunts.
- Understanding the pathophysiology of PDE is crucial for diagnosing uncommon embolic events.
Observation:
- Two cases of PDE were identified, presenting with distinct clinical scenarios.
- One patient experienced shock and cerebral infarction, while the other developed middle cerebral artery occlusion during an angiographic procedure.
Findings:
- Both diagnosed cases of PDE were treated with thrombolytic and anticoagulant therapies.
- Successful recovery was observed in both patients following intervention.
Implications:
- This case series underscores the varied clinical presentations of paradoxical embolism.
- Emphasizes the critical role of thorough patient history and physical examination in the early and accurate diagnosis of PDE.

