Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Sarcomere01:08

The Sarcomere

17.5K
A sarcomere is a microscopic segment repeating in a myofibril. The sarcomere fundamentally consists of two main myofilaments: thick filaments called myosin and thin filaments called actin. These filaments interact by sliding past each other in response to stimulus. In addition to myosin and actin, several other proteins, such as tropomyosin, troponin, titin, nebulin, myomesin, α-actinin, and dystrophin, play crucial roles in regulating, structuring, and functioning of the sarcomere.
Each...
17.5K
Self-Presentation: Self-Monitoring and Self-Handicapping02:05

Self-Presentation: Self-Monitoring and Self-Handicapping

44.9K
People can go to great lengths to protect their self-image and present themselves in ways that they want others to see them. Sociologist Erving Goffman presented the idea that a person is like an actor on a stage. Calling his theory dramaturgy, Goffman believed that we use “impression management” to present ourselves to others as we hope to be perceived. Each situation is a new scene, and individuals perform different roles depending on who is present (Goffman, 1959). Think about...
44.9K
Agonism and Antagonism: Quantification01:14

Agonism and Antagonism: Quantification

1.2K
When drugs are administered, they can elicit either an agonist or antagonist effect on the body. Agonism occurs when a drug activates a specific receptor, triggering a biological response. On the other hand, antagonism happens when a drug binds to the same receptors but blocks their activation, thereby preventing a biological response.
To quantify these effects, researchers use a dose-response curve, which provides valuable information about the potency and efficacy of a drug. Potency refers to...
1.2K
Sympathetic Signaling01:31

Sympathetic Signaling

2.6K
Sympathetic signaling, a vital part of the autonomic nervous system, plays a crucial role in mobilizing the body's resources in response to stress or emergencies. It involves the transmission of nerve impulses from sympathetic preganglionic fibers to postganglionic fibers. This results in the release of specific neurotransmitters and activation of adrenergic receptors.
Sympathetic preganglionic fibers release the neurotransmitter acetylcholine (ACh) onto the ganglionic neurons in the...
2.6K
The Thoracic Cage: Ribs01:20

The Thoracic Cage: Ribs

9.8K
Ribs are curved, flattened bones forming the thoracic cavity wall with the thoracic muscles. There are 12 pairs of thoracic ribs. The posterior ends of all the ribs articulate with the T1–T12 thoracic vertebrae. In contrast,the anterior ends of most ribs attach to the sternum via their costal cartilages.
Parts of a Typical Rib
A typical rib has a head, neck, and body. The posterior end of the rib is called the head, followed by a narrow neck. The head articulates primarily with the costal...
9.8K
Bones of the Upper Limb: Radius01:09

Bones of the Upper Limb: Radius

10.5K
The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a...
10.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ataxia Global Initiative recommend MRI end-points for clinical trials in ataxias.

Nature reviews. Neurology·2026
Same author

Longitudinal Dynamics of Polyglutamine-Expanded ATXN3 in Biofluids of Spinocerebellar Ataxia Type 3.

Movement disorders : official journal of the Movement Disorder Society·2026
Same authorSame journal

Ozzy Osbourne and Parkinson's disease: from darkness to awareness.

Arquivos de neuro-psiquiatria·2026
Same author

"Expert Commentary on Segmental brainstem myoclonus in ADCK3-related ataxia".

Parkinsonism & related disorders·2026
Same author

Cerebral palsy in art and literature throughout history.

Arquivos de neuro-psiquiatria·2026
Same author

Isaac Newton's description of the optic chiasm.

Arquivos de neuro-psiquiatria·2026
Same journal

Prevalence and predictors of low bone mineral density in Myasthenia gravis.

Arquivos de neuro-psiquiatria·2026
Same journal

Hypochondriasis, somatic amplification, and pain beliefs in patients with medication overuse headache.

Arquivos de neuro-psiquiatria·2026
Same journal

The weight of genotype on the clinical presentation of COQ7-related hereditary motor axonal neuropathy: a case series and literature review.

Arquivos de neuro-psiquiatria·2026
Same journal

Rituximab as a sustainable high-efficacy solution for multiple Sclerosis in Brazil.

Arquivos de neuro-psiquiatria·2026
Same journal

Reply to: "Sleep quality is influenced by multiple factors and cannot be reduced to the volume of pineal gland calcification".

Arquivos de neuro-psiquiatria·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
12:43

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS

Published on: February 21, 2011

36.1K

Charcot's irony and sarcasm.

Hélio A G Teive1, Francisco M B Germiniani1, Renato P Munhoz2

  • 1Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Medicina, Serviço de Neurologia, Curitiba PR, Brasil.

Arquivos De Neuro-Psiquiatria
|June 29, 2017
PubMed
Summary
This summary is machine-generated.

Jean-Martin Charcot, the father of modern neurology, was a reserved figure. However, understanding his personality reveals complexities in his neurological research and work style.

More Related Videos

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

33.4K
Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
07:43

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons

Published on: January 7, 2019

7.4K

Related Experiment Videos

Last Updated: Feb 27, 2026

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
12:43

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS

Published on: February 21, 2011

36.1K
Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

33.4K
Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
07:43

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons

Published on: January 7, 2019

7.4K

Area of Science:

  • Neurology
  • Neuroscience history

Background:

  • Jean-Martin Charcot is recognized as the father of modern neurology.
  • He was the first neurologist to hold a professorship dedicated to nervous system diseases.

Discussion:

  • Biographers often portray Charcot as austere, reserved, shy, and impassive.
  • This portrayal contrasts with documented instances revealing a wry and sarcastic side.

Key Insights:

  • Charcot's personality was more complex than his public image suggested.
  • Understanding his full character provides deeper insight into his neurological contributions.

Outlook:

  • Further exploration of historical figures in neurology can illuminate scientific progress.
  • Analyzing personality traits alongside professional achievements offers a richer understanding of scientific legacies.