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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Typhoid fever, caused by *Salmonella Typhi*, is prevalent in developing nations.
  • Typical symptoms include fever, vomiting, anorexia, and abdominal pain.
  • Hepatic involvement is an uncommon but serious complication.

Observation:

  • A case report details a 26-year-old male presenting with fever, jaundice, and ascites.
  • Initial Widal test titres were within normal limits (1:80).
  • Ascitic fluid culture confirmed the presence of *Salmonella Typhi*.

Findings:

  • The patient's presentation mimicked other causes of ascites and jaundice.
  • Despite normal Widal titres, *Salmonella Typhi* was identified as the causative agent.
  • Prompt antibiotic therapy led to clinical improvement.

Implications:

  • This case highlights the importance of considering typhoid fever in endemic areas, even with atypical presentations.
  • Ascitic fluid culture is a valuable diagnostic tool when Widal tests are inconclusive.
  • Effective antibiotic management can lead to favorable outcomes in severe typhoid fever cases.