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A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
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Healthcare Associated Infections II: Preventive Measures01:22

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Related Experiment Video

Updated: Feb 27, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
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Severe Puerperal Sepsis-A Simmering Menace.

Sheeba Marwah1, Sonam R Topden2, Manjula Sharma3

  • 1Research Officer, Department of Obstetrics and Gynecology, Vmmc and Safdarjung Hospital, New Delhi, India.

Journal of Clinical and Diagnostic Research : JCDR
|June 30, 2017
PubMed
Summary

Puerperal sepsis remains a major cause of preventable maternal death in India, particularly among referred cases. Unsafe delivery and abortion practices significantly contribute to high mortality rates from this condition.

Keywords:
Maternal morbidityMaternal mortalityPostabortal periodPuerperium

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • Sepsis is a leading cause of preventable maternal death globally, with significant disparities in developing countries like India.
  • Poverty exacerbates maternal health inequalities, contributing to high maternal mortality rates due to sepsis.

Purpose of the Study:

  • To investigate the incidence, risk factors, and mortality associated with puerperal sepsis in Indian women.
  • To analyze clinical data from a tertiary care facility to understand puerperal sepsis outcomes.

Main Methods:

  • A retrospective study analyzed case records of women with puerperal sepsis at VMMC and Safdarjung Hospital, New Delhi.
  • Inclusion criteria focused on postpartum or post-miscarriage patients presenting with fever and specific clinical signs within 42 days.
  • Data on demographics, clinical presentation, management, complications, and mortality were extracted and analyzed.

Main Results:

  • The study identified 33 cases of puerperal sepsis, with 90% being referred patients.
  • Key risk factors included anemia, prolonged labor, delivery by untrained personnel, and unsafe abortions.
  • Surgical intervention was needed in 75% of cases, and the mortality rate was high at 70%, primarily due to multiorgan failure.

Conclusions:

  • Maternal mortality from puerperal sepsis is alarmingly high in the studied population.
  • Lack of safe and hygienic practices during delivery and abortion are critical contributing factors to puerperal sepsis and its fatal outcomes.