Copper Deficiency Myelopathy After Upper Gastrointestinal Surgery

Area of Science:

• Gastroenterology and Neurology
• Nutritional Science

Background:

• Adequate nutrient absorption relies on a healthy alimentary canal.
• Upper gastrointestinal surgery can disrupt nutrient absorption, potentially causing micronutrient deficiencies.
• Copper deficiency is a recognized complication of Roux-en-Y gastric bypass surgery, though its neurological sequelae are often underreported.

Observation:

• This case report details a patient who developed copper deficiency myelopathy.
• The condition presented similarly to subacute combined degeneration of the spinal cord.
• The myelopathy occurred after upper gastrointestinal bypass surgery for gastric ulceration, compounded by poor nutrition.

Findings:

• Copper deficiency myelopathy is a serious neurological complication following upper gastrointestinal bypass surgery.
• The clinical presentation can mimic other spinal cord disorders, delaying diagnosis.
• Inadequate nutritional intake post-surgery significantly contributes to the development of deficiency states.

Implications:

• Highlights the importance of monitoring copper levels in patients with a history of upper gastrointestinal bypass surgery.
• Emphasizes the need for early recognition and intervention to prevent irreversible neurological damage.
• Underscores the critical role of nutritional support in managing patients post-bariatric or gastrointestinal surgeries.