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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

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Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling

Lunyi Li1,2, Xingdong Guo1,2, Xiaoshan Shi1,2

  • 1State Key Laboratory of Molecular Biology, Chinese Academy Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

Proceedings of the National Academy of Sciences of the United States of America
|June 30, 2017
PubMed

Keywords:
LckT-cell receptorinitial phosphorylationionic interactionsubstrate selectivity

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