Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.1K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.1K
Bulimia Nervosa01:30

Bulimia Nervosa

874
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
874
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

3.1K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
3.1K
Anorexia Nervosa01:28

Anorexia Nervosa

1.6K
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
1.6K
Pleiotropy01:33

Pleiotropy

43.6K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
43.6K
Obesity01:24

Obesity

1.4K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative gut microbiota profiling of obese and normal-weight indian adults using 16S rRNA sequencing.

Molecular biology reports·2026
Same author

A noval 4D graph temporal brain network model for EEG-based depression detection.

Health information science and systems·2026
Same author

Assessment of Rhodococcus sp. (MG1) induced biochemical alterations and genotoxicity in Spodoptera litura.

Scientific reports·2026
Same author

Role of Low-Dose Infliximab for Inflammatory Complications of Central Nervous System Tuberculosis: A Retrospective Cohort Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Sesamol as a multifunctional antioxidant in tissue injury and repair: mechanistic insights and therapeutic perspectives.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Neurovascular compression in patients with stress-related somatic complaints.

Industrial psychiatry journal·2026
Same journal

Marital adjustment, psychological distress, and Internet addiction among married couples in an urban community: A cross-sectional study.

Industrial psychiatry journal·2026
Same journal

Neuropsychiatric presentation of Wernicke-Korsakoff syndrome secondary to chronic alcohol dependence.

Industrial psychiatry journal·2026
Same journal

Theoretical underpinnings of flow and its relation with academic engagement: A narrative review.

Industrial psychiatry journal·2026
Same journal

Association of sleep quality and urinary melatonin levels with endometrial cancer: A case control pilot study.

Industrial psychiatry journal·2026
Same journal

Dengue: A cause for anxiety in endemic regions, a Thai experience.

Industrial psychiatry journal·2026
Same journal

Enhancing well-being and managing depression in alcohol dependence patients through well-being therapy.

Industrial psychiatry journal·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

2.5K

Meige's syndrome.

Priyanka Gautam1, Manjeet Singh Bhatia1, Jaswinder Kaur1

  • 1Department of Psychiatry, University College of Medical Sciences and GTB Hospital, New Delhi, India.

Industrial Psychiatry Journal
|June 30, 2017
PubMed
Summary
This summary is machine-generated.

Meige's syndrome, a condition causing involuntary eyelid closure and jaw spasms, has no cure. This case study shows promising results using tetrabenazine for treatment.

Keywords:
EtiologyMeige's syndromeoromandibular dystoniatetrabenazinetreatment

More Related Videos

Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease with Fibrosis
06:26

Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease with Fibrosis

Published on: July 18, 2025

981
Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
08:03

Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice

Published on: April 15, 2014

84.1K

Related Experiment Videos

Last Updated: Feb 27, 2026

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

2.5K
Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease with Fibrosis
06:26

Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease with Fibrosis

Published on: July 18, 2025

981
Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
08:03

Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice

Published on: April 15, 2014

84.1K

Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Meige's syndrome is characterized by idiopathic blepharospasm and oromandibular dystonia.
  • Its precise etiology remains unknown, with several hypotheses proposed.
  • The leading hypothesis involves dopaminergic and cholinergic hyperactivity.

Observation:

  • This report details a patient diagnosed with Meige's syndrome.
  • The patient presented with symptoms of blepharospasm and oromandibular dystonia.

Findings:

  • The patient's condition showed a positive response to treatment with tetrabenazine.
  • Tetrabenazine, a VMAT2 inhibitor, targets dopaminergic pathways.

Implications:

  • This case suggests tetrabenazine as a potential therapeutic option for Meige's syndrome.
  • Further research is warranted to explore tetrabenazine's efficacy and safety in larger patient cohorts.
  • Understanding the dopaminergic and cholinergic mechanisms may lead to novel treatment strategies.