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Related Concept Videos

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Feb 27, 2026

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
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Gait Implications of Visual Field Damage from Glaucoma.

Aleksandra Mihailovic1, Bonnielin K Swenor1, David S Friedman1

  • 1Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.

Translational Vision Science & Technology
|June 30, 2017
PubMed
Summary

Glaucoma patients exhibit altered gait patterns, specifically increased stride-to-stride variability, linked to visual field loss. These gait changes may identify individuals at higher risk of falls, informing prevention strategies.

Keywords:
gaitglaucomamobilityvisual field

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Area of Science:

  • Ophthalmology
  • Gerontology
  • Biomechanics

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Older adults are at increased risk of falls, and glaucoma may exacerbate this risk.
  • Gait disturbances are known predictors of falls in the elderly.

Purpose of the Study:

  • To investigate the relationship between glaucoma severity and specific gait parameters relevant to fall risk.
  • To identify gait features that can help stratify fall risk in glaucoma patients.

Main Methods:

  • 239 patients with glaucoma underwent gait analysis using the GAITRite Electronic Walkway under normal and dual-task (carrying) conditions.
  • Integrated visual field (IVF) sensitivity was measured.
  • Multiple linear regression models were used to assess associations between gait parameters and IVF sensitivity, controlling for covariates.

Main Results:

  • Worse integrated visual field (IVF) sensitivity correlated with a wider base of support under normal walking.
  • Under dual-task conditions, worse IVF sensitivity was associated with slower gait speed, shorter step/stride length, and greater left-right drift.
  • Increased stride-to-stride variability in step length, stride length, and stride velocity was significantly associated with worse IVF sensitivity.

Conclusions:

  • Glaucoma severity, particularly visual field loss, is linked to gait parameters associated with increased fall risk.
  • Gait variability appears to be a key indicator of fall risk in glaucoma patients.
  • Gait analysis holds potential for identifying high-risk individuals and guiding the development of fall prevention interventions in glaucoma care.