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Updated: Feb 27, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
Published on: August 15, 2025
Hypoglycaemic and hypolipidaemic properties of peach gum polysaccharides
Shengjun Wu1,2,3,4, Mingsheng Lu1,2,3,4, Shujun Wang5,6,7,8
1College of Marine Life and Fisheries, Huaihai Institute of Technology, 59 Cangwu Road, Haizhou, Lianyungang, 222005, China.
Abstract:
Hyperglycaemia and hyperlipidaemia are major risk factors for coronary artery diseases and atherosclerosis. Peach gum polysaccharides (PGPs) possess various bioactivities. In this study, PGPs were extracted with thermostable α-amylase and investigated in terms of hypolipidaemic and hypoglycaemic activities. KKAy mice were gavaged once daily with either PGPs or distilled water (control group) for 3 weeks. Oral administration of PGPs decreased the levels of serum triglyceride, cholesterol low-density lipoprotein cholesterol, fasting blood glucose, plasma insulin, C-peptide, and HbAlc in mice. Moreover, treatment with PGPs increased the insulin sensitivity index in KKAy mice. Results indicated that PGPs possess significant hypoglycaemic effects and could be developed as a drug for preventing hyperlipidaemia and hyperglycaemia.
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