Related Experiment Video
Updated: Feb 27, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
Comparison of Complications Following Laparoscopic and Endoscopic Gastrostomy Placements
Sara L Zettervall1, Jeremy L Holzmacher2, Michal Radomski2
1Department of Surgery, George Washington University School of Medicine and Health Sciences, 2150 Pennsylvania Ave. NW, Suite 6B, Washington, DC, 20037, USA. slzettervall@gmail.com.
Insights
Laparoscopic gastrostomy (LG) placement is as safe as percutaneous endoscopic gastrostomy (PEG) placement in adults, even with higher patient comorbidities. Further research should identify predictors for superior LG outcomes in specific patient groups.
Area of Science:
- Gastroenterology
- Surgical Procedures
- Medical Device Placement
Background:
- Enteral access is crucial for patients unable to tolerate oral feeds.
- Percutaneous endoscopic gastrostomy (PEG) and laparoscopic gastrostomy (LG) are common methods for enteral access.
- Limited comparative data exists for PEG versus LG outcomes in adult populations.
Purpose of the Study:
- To compare complication rates between PEG and LG placements in adult patients.
- To identify factors influencing outcomes in patients undergoing gastrostomy procedures.
Main Methods:
- Retrospective chart review of 224 adult patients (164 PEG, 60 LG) from 2007-2014.
- Comparison of patient demographics, comorbidities, and Charlson Comorbidity Index (CCI).
- Logistic regression analysis to determine predictors of complications.
Main Results:
- LG patients had higher rates of prior surgery and age-adjusted CCI.
- Return to operating room was more frequent after PEG (5.5%) than LG (0%), though not statistically significant.
- No difference in 30-day mortality; however, higher CCI predicted mortality.
Conclusions:
- Laparoscopic gastrostomy (LG) demonstrates comparable safety to percutaneous endoscopic gastrostomy (PEG), despite higher patient comorbidity.
- Further research is needed to identify patient-specific factors that may predict superior outcomes with LG placement.
- Optimizing patient selection for LG could enhance post-operative outcomes.
Introduction:
Percutaneous endoscopic gastrostomy (PEG) and laparoscopic gastrostomy (LG) placements provide enteral access to patients unable to tolerate oral feeds. Limited data comparing PEG and LG outcomes is available in adults. This study compares complications between PEG and LG placements.
Materials And Methods:
A retrospective chart review was completed for patients undergoing PEG or LG placement at a single academic center between 2007 and 2014. Patient demographics, comorbidities, and Charlson Comorbidity Index (CCI) were compared. Logistic regression was utilized to identify independent predictors for complication.
Results:
Two hundred and twenty-four patients (164 PEGs and 60 LGs) were evaluated. Patients undergoing LG had a higher incidence of prior surgery (42 vs 20%; P < 0.01) and age-adjusted CCI (5 vs 4; P = 0.01). Return to the OR was more common following PEG than LG (5.5 vs 0%) but did not achieve significance (P = 0.12). There were no differences in 30-day mortality; however, age-adjusted CCI was predictive of 30-day mortality (OR 1.3, 95% CI 1.1-1.6).
Conclusion:
Despite increased comorbidities, LG tubes are at least as safe as PEGs. Research should focus on identifying predictive factors associated with post-operative complications to identify which patients would have superior outcomes with LG placement.
More Related Videos
03:32Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
Published on: December 27, 2024
04:05Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures V: ERCP
Patient...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...