Related Experiment Video
Updated: Feb 27, 2026
Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Correlations between 10-year risk of death from cardiovascular diseases
Anna Kawińska-Hamala1, Andrzej Kawiński, Krzysztof Stanek
1Clinic of Electrocardiology, Medical University of Lodz, Poland. anna_kaw@wp.pl.
Insights
The 10-year risk of fatal cardiovascular disease (CVD) is linked to osteoporosis and fracture risk. This finding can help identify elderly patients needing enhanced cardiac care protocols.
Area of Science:
- Gerontology
- Cardiology
- Osteoporosis Research
Background:
- Osteoporosis and cardiovascular diseases (CVD) are prevalent in the elderly.
- Both conditions share common risk factors.
- Identifying correlations can improve patient management.
Purpose of the Study:
- To evaluate the correlation between 10-year risk of death from CVD and 10-year bone fracture risk (FRAX).
Main Methods:
- 79 patients (50-83 years) with and without osteoporosis were analyzed.
- Bone mineral density (BMD) was assessed using densitometry.
- Cardiovascular risk (Euro Heart Score - EHS) and fracture risk (FRAX) were calculated.
Main Results:
- Patients with osteoporosis had a higher average EHS.
- EHS correlated negatively with BMD (Neck, Total Hip, L2-L4 T-scores).
- EHS positively correlated with major osteoporotic fracture risk (MOFR) and hip fracture risk (HFR).
Conclusions:
- A significant correlation exists between 10-year fatal CVD risk and osteoporosis.
- The 10-year risk of osteoporotic fractures is also linked to CVD risk.
- These findings aid in identifying patients for extended cardiotherapy.
Introduction:
Osteoporosis and cardiovascular diseases (CVD) are more common in the elderly population and have similar risk factors. THE GOAL: was an evaluation of the correlation between 10-year risk of death from CVD and 10-year bone fracture risk (FRAX).
Material And Methods:
A total of 79 patients of the Regional Centre of Menopause and Osteoporosis of the Military Teaching Hospital in Lodz (Poland), aged 50-83 years, consulted for osteoporosis were divided into two groups: study group - with osteoporosis (O; T-score ≤ -2.5 SD) and control - without osteoporosis (T-sc > -2.5). Bone mineral density was evaluated by densitometric scanning of spine (L2-L4 T-score) and/or femoral neck (Neck T-score) and/or total hip (Total Hip T-score). Total cholesterol (TC), fasting glucose, arterial blood pressure, medical history, and family history were obtained. The risk of fatal-CVD was assessed by Euro Heart Score (EHS), and major osteoporotic (MOFR) and hip fracture risk (HFR) by the FRAX scale.
Results:
80% of the patients (32/40) with osteoporosis and 51% (20/39) of the patients without osteoporosis revealed a HeartScore ≥ 5%. There was correlation in the group of all patients between EHS and Neck T-score (p < 0.05; Spearman rank correlation coefficient (Rs) = -0.3806), L2-L4 T-score (p < 0.05; Rs = -0.2891), and Total Hip T-score (p < 0.005; Rs = -0.3561), and in the control group - between EHS and Neck T-score (p < 0.05; Rs = -0.3502). There was a 2.33% difference between the average EHS level to the disadvantage of patients with osteoporosis (p < 0.05). EHS positively correlated with MOFR (p < 0.001) and HFR (p < 0.001) in the whole study popula-tion and with MOFR (p < 0.05) and HFR (p < 0.01) in the group of osteoporotic patients. There were differences between groups in TC (p < 0.001) and BMI (p < 0.001) levels.
Conclusions:
The 10-year risk of fatal-CVD correlated with osteoporosis and with the 10-year osteoporotic fracture risk. This conclusion may help identify patients who require extended cardiotherapy protocols.
Related Concept Videos
01:12Relative Risk
01:30Coronary Artery Disease I: Introduction
01:26Coronary Artery Disease IV: Preventive Measures
01:12Hazard Ratio
For example, in a clinical trial...
01:25Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
02:20Correlations